|"Seattle is home to world class facilities, like the Mako Ballistics Weapon Laboratory and the Tarsus Academies Intermediate Training Facility."|
|- Deus Ex: Invisible War description|
In 2027, Seattle was one of several American "fortress cities" under heavy enforcement due to the spiral of economic and civil unrest, rising terrorism, draconian governance and subsequent dissent in the United States.
After 2052 and the Collapse, Seattle chose not to raze its ruins. Instead, Seattle erected large pillars on which they placed a great platform. On this platform, they would build Upper Seattle, with the old ruins now called Lower Seattle lying beneath it. The platform thus divided the city between the rich above, and the poor below, the latter of which became a haven for looters, raiders and those rejected by society. Both parts are connected by a massive elevator, called the Inclinator, that carries people and objects between the two parts.
In 2071, Seattle's WTO charter was ratified to the dismay of many Lower Seattle citizens, making Upper Seattle a WTO-controlled enclave, and allowing Seattle to prosper and become home to world-class facilities like the Mako Ballistics weapons lab (which must be accessed by aircraft) and one of the Tarsus academies. While Upper Seattle is largely successful as a result and has a thriving economy (albeit controlled by the Illuminati), most of Lower Seattle still lives in poverty, driving many to join The Order Church.